This dashboard takes a close look at the trending of the top sequencing platforms with which researchers are publishing and how the platforms are trending over time and by region.
Contact Mapping Global Research Profile
The introduction of chromosome conformation capture (3C) in 2002 provided a breakthrough technology to researchers seeking to better understand the structural properties and interactions of chromosomes and how they impact gene regulation. 3C techniques have been used to understand the structure of chromatin, and how it changes in pathological conditions such as cancer.
Most 3C methods use formaldehyde cross-linking and digestion with a restriction enzyme, however the downstream readout approaches vary and have evolved with technology over time leading to numerous distinct methods including: 3C (chromosome conformation capture), 4C (circularized chromosome conformation capture), 5C (Carbon-Copy Chromosome Conformation Capture), ChIP Loop, and ChIA PET.
Each of these provides slightly different advantages and disadvantages, but have their place in structural studies.
Inside this Dashboard
This Research Profile summarizes the world’s top authors and institutions publishing work with 3C methods. Inside it, you’ll find:
- Top publishing authors using 3C-based methods in their studies
- Top institutions where labs are using 3C-based methods in their studies
- Author and institution 3C usage trending over time
- Highest cited authors and institutions using 3C-based methods and
- A comprehensive list of publications from top authors using 3C methods ranked by their publications’ citation volume